MONTROVIA – Africa continues to experience elevated MPOX cases as Africa reports that Uganda reports the most confirmed daily cases in the region, according to the World Health Organization (WHO). The report warns that “wherever there is no rapid inclusion of an MPOX outbreak,” making it difficult to stop human-to-human transmission and could endanger “sustained transmissions in the community.”
Uganda surpassed the Democratic Republic of the Congo as the most intense nation in 200-300 cases a week, but the report continues to report the most “cumulative MPOX cases” in Africa in 2025, with Clade IA and IB being the most dominant.
Previously, Uganda’s Ministry of Health announced that more than 50 cases have been killed in the country and more than 40 confirmed cases. Officials said Kampala and other cities have filed the most lawsuits, with authorities implementing “surveillance, case management and public awareness efforts to contain the virus.”
According to a WHO report, Burundi continues to observe a downward trend in confirmed cases. This is “we have less than 50 new confirmed cases per week.”
Sierra Leone has seen an increase in confirmed MPOX cases, with over 200 new confirmed cases reported “the most recent week.” The report highlights an increase in domestic transmission.
In August 2024, the World Health Organization and the African Centre for Disease Control and Prevention (Africa CDC) each declared MPOX a public health emergency due to a rapid increase in case numbers. However, the African CDC has announced that it will convene a panel of experts to decide whether it should be classified as an emergency due to the indication of both infectious disease and downturn in countries affected by Africa.
Meanwhile, there has been an increase in vaccinations against the disease, with over 500,000 doses being administered in seven countries. “88% of the total doses were administered in the Democratic Republic of the Congo, where the vaccination strategy has been revised in light of limited vaccine supply,” the WHO report states.
